Synthesis and Characterization of some New 3,3'-(1,4-Phenylene) Bis (1-(4-Aminophenyl) Prop-2-en-1-one) Amide Derivatives

Abstract

A new amide derivative series [A1-A8] was prepared in good yield by direct reflux condensation of bis-chalcone [3,3'-(1,4-phenylene) bis (1-(4-aminophenyl) prop-2-en-1-one)] with different carboxylic acids and acrylamide in the presence of a suitable solvent and amount of sodium hydroxide (NaOH). The structures of the synthesized amide were characterized by various spectral techniques, including FTIR (Fourier-Transform Infrared Spectroscopy), 1H-NMR (Proton Nuclear Magnetic Resonance Spectroscopy), and mass spectroscopy, and the resultant spectra confirmed the expected structure of the prepared bis-chalcone derivative.