Estimation of Some Hematological Parameters, Liver Enzymes and Iron Mineral in Adult of Celiac Disease Patients

Abstract

Celiac disease is one of the most prevalent chronic illnesses. It is produced due to gluten, a protein found in wheat, rye, and barley that damages the villi, so the body cannot     adequately absorb nutrients. This s tudy was undertaken to determine of some hematological parameters, liver enzyme and iron (Fe) in celiac disease patients compared with the healthy group.  The results indicated a high significantly increase (p ≤ 0.01) in levels of ALT (alanine transferase), ALP (alkaline phosphatase), ESR (erythrocyte sedimentation rate), AST (aspartate transferase) in age category (41-60) and WBC (white blood cells) in age category (41-60), while significantly increased (p ≤ 0.05) in levels of AST and WBC in age category (20-40) in celiac disease patients as compared with healthy group. High significantly decreased (p ≤ 0.01) in levels of hemoglobin in age category (20-40), RBC (red blood cells) and Fe, while levels of hemoglobin in age category (41-60) was significantly decreased (p ≤ 0.05) in celiac disease patients as compared with healthy group. In celiac disease patients of age category (20-40) as compared with age category (41-60), there was a high significant difference (p ≤ 0.01) in ESR, AST and Fe and significant difference (p ≤ 0.05) in ALT and ALP, while no significant in hemoglobin, RBC and WBC in celiac disease patients of age category (20-40) as compared with age category (41-60).  This study concludes that untreated celiac disease causes nutrient deficiencies due to malabsorption, which causes anemia, inflammations, and elevated liver enzymes.